CRC 1349/2: Fluorine-Specific Interactions: Fundamentals and Functions

The aim of the CRC 1349 is to understand, control and apply the complex interactions that can arise from fluorinated groups in chemical systems and are denoted as Fluorine-Specific interactions. This includes systems with H???F Interactions, with Acceptorcontrolled Properties, e.g., in fluorinated Lewis-acids, and Interactions with fluorous Systems such as those encountered between (per-)fluorinated alkane groups. Interactions on a molecu-lar scale differ significantly from collective interactions due to mutually influencing, non-additive effects that exist on surfaces or in liquid phases. Therefore, the investigated systems range from single molecules through various ensembles to condensed phases or interfaces. The CRC focuses on the influences of the investigated interactions on a wide range of physicochemical properties and chemical reactivities. This includes the effects of Fluorine-Specific interactions on the properties of functional materials, the mechanisms of catalytic processes, and the function of biochemical systems and pharmaceuticals. For this purpose, the comprehensive expertise of the working groups involved in synthesis/biosynthesis, analysis/spectroscopy, and theory/modeling is linked in a complementary and synergistic manner to establish an understanding of Fluorine-Specific interactions, their con-ceptual foundation, and their numerous consequences and to translate all these into functional systems.